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Possible side effects

RYBELSUS® may cause side effects, although not everybody gets them. 

The most common side effects observed in clinical trials were nausea, diarrhoea, and vomiting, with 15%, 10%, and 7% of patients, respectively, reporting one or more incidences. Most events were mild to moderate in severity and of short duration.1

You can learn more about potential side effects of treatment with RYBELSUS® by reviewing the full package leaflet. You can also contact your HCP if you want advice on how to manage side effects.

Tips for handling nausea

If you do experience nausea, here are some things that may help: 

Try to

  • Eat smaller portions, perhaps with healthy snacks in between.
  • Eat slowly.
  • Stay hydrated. When nausea appears, drinking cold water can help.
  • Listen to your body: Stop eating at the first sign of fullness.
Avoid
  • Fried or fatty foods.
  • Overly sweet or spicy foods.
  • Intake of large amount of fibrous food in a single meal; distribute them throughout the day.
  • Drinking alcohol and smoking cigarettes.

Download the patient leaflet for more information about taking or using RYBELSUS®.

For questions about managing your diabetes and taking your daily RYBELSUS®, talk to your health care professional.

Read patient leaflet
References

RYBELSUS® [summary of product characteristics]. Bagsværd, Denmark: Novo Nordisk A/S; REF- 53798; December 2021.

Piepoli MF, Hoes AW, Agewall S, et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice. European Heart Journal. 2016;37:2315–2381.

Davies MJ, D’Alessio DA, Fradkin J, et al. Management of hyperglycaemia in type 2 diabetes, 2018. A Study of Diabetes (EASD). Diabetologia. 2018;61:2461–2498.

American Diabetes Association. Diabetes A to Z: What You Need to Know About Diabetes—Simply Put. 7th ed. Alexandria, VA: American Diabetes Association; 2016. 

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