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FAQ

If you find you have questions, chances are someone else has asked the same thing. Many answers to the most commonly asked questions can be found here. If you have additional questions, please contact your doctor or nurse. 

How to store RYBELSUS®?

Store in the original package in order to protect from light and moisture. This medicine does not require any special temperature storage conditions.1

Why is it important to take my pill on an empty stomach? 

Taking RYBELSUS® on an empty stomach is important, as any kind of food, beverages, or oral medications may prevent RYBELSUS® from entering your bloodstream and taking effect.1

Can I take RYBELSUS® with anything other than water? 

No, the effectiveness of RYBELSUS® has not been studied with any other type of drink. 

Why is it important to wait at least 30 minutes before eating, drinking, or taking other oral medication?

RYBELSUS® may not work properly if you eat, drink, or take oral medication within 30 minutes after taking RYBELSUS®.1 

What should I do if I forgot to take a dose? 

If you forgot to take a dose, the missed dose should be skipped. The next dose should be taken the following day. Do not take a double dose.1

Do I need to take my pill at the same time every day? 

No, it is important to take RYBELSUS® on an empty stomach, but you do not need to take it at the same time everyday.1

Can two RYBELSUS® pills be taken at the same time to increase dose? 

No. It is not recommended to take two 7 mg pills instead of one 14 mg pill. Because of the way RYBELSUS® is absorbed, the pill is intended to sit in the stomach without the presence of any other oral medications (along with absence of food and other beverages). Therefore, taking multiple pills at the same time is not recommended.

Can I experience hypoglycaemia?

Though unlikely, low blood glucose (hypoglycaemia) can occur with RYBELSUS®, particularly if you are taking any blood-glucose-lowering medicines, like insulin and/or sulfonylureas in combination with RYBELSUS®.1

Signs and symptoms of hypoglycaemia may include: cold sweat, headache, fast heartbeat, feeling sick and/or hungry, dizziness, feeling sleepy and/or weak, nervousness, and shaking.1

If you think you are experiencing hypoglycaemia while taking RYBELSUS®, contact your doctor or nurse for advice. 

Will it interfere with my current medications?

Talk to your doctor or nurse to see if RYBELSUS® can interfere with your current medication. 

Download the patient leaflet for more information about taking or using RYBELSUS®.

For questions about managing your diabetes and taking your daily RYBELSUS®, talk to your health care professional.

References

RYBELSUS® [summary of product characteristics]. Bagsværd, Denmark: Novo Nordisk A/S; REF- 53798; December 2021.

Piepoli MF, Hoes AW, Agewall S, et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice. European Heart Journal. 2016;37:2315–2381.

Davies MJ, D’Alessio DA, Fradkin J, et al. Management of hyperglycaemia in type 2 diabetes, 2018. A Study of Diabetes (EASD). Diabetologia. 2018;61:2461–2498.

American Diabetes Association. Diabetes A to Z: What You Need to Know About Diabetes—Simply Put. 7th ed. Alexandria, VA: American Diabetes Association; 2016. 

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